Four years ago, audiences were invited to come along with male nurse Greg (a.k.a. Gaylord) Focker on a weekend as he lost his luggage, set the backyard on fire, went a little over-the-top in a game of water volleyball, spray painted the cat and was administered a lie-detector test by Jack Byrnes, his girlfriend’s father (who turned out to be not a horticulturalist, but an ex-CIA operative reluctant to allow Greg into The Byrnes Family Circle of Trust) in the blockbuster comedy Meet the Parents.

The film became the runaway hit of the fall of 2000, tallying more than $300 million worldwide.

Now, Greg has managed to earn his way inside the Circle of Trust and things are going great. He and his fiancée Pam are excitedly planning their wedding and there’s only one tiny, itsy-bitsy little thing left to smooth the way to the altar: the future in-laws need to spend a weekend together.

So, Greg and Pam climb aboard Jack’s new state-of-the-art RV (with the Kevlar-reinforced hull and the two-inch Plexiglas windows) for a trip to Focker Isle, the Cocoanut Grove domicile of Bernie and Roz Focker. The next 48 hours will provide the parents of the intended bride and groom a little time to get to know each other, but more importantly, give Jack the opportunity to study Greg’s parents.

Things start off well enough, but that’s before Jack discovers that the lawyer and doctor Greg presented are, in fact, a liberal stay-at-home dad and a senior citizens’ sex therapist. Then there’s the RV toilet episode, the overly zealous game of touch football, the saucy Cuban caterer with the secret, the incident with the toddler and the glue... Ready or not, it’s time to Meet the Fockers...it’s just one weekend together. What could possibly go wrong?